Acquired immunity to Ancylostoma ceylanicum in hamsters

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The immune response of male DSN hamsters to a primary infection with Ancylostoma ceylanicum.

The immune response of hamsters to a chronic hookworm infection has been investigated. Ancylostoma ceylanicum caused long term infections in hamsters which were associated with prominent changes in secondary lymphoid organs. The mesenteric lymph nodes and spleens increased rapidly in size stabilizing at approximately 3-4 times the weight in control animals by weeks 3-7. Cells from both the mese...

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Necator americanus and Ancylostoma ceylanicum: development of protocols for dual infection in hamsters.

Two-day-old baby hamsters were infected initially with the infective larvae of hamster-adapted human hookworm, Necator americanus (NaL3). After a specified period they were again infected orally with infective larvae of Ancylostoma ceylanicum (AcL3). Three weeks after the second infection they were killed and the establishment of N. americanus and A. ceylanicum was assessed. The effect of diffe...

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Evaluation of Biochemical, Hematological and Parasitological Parameters of Protein-Deficient Hamsters Infected with Ancylostoma ceylanicum

BACKGROUND Hookworms infect millions of people worldwide and can cause severe clinical symptoms in their hosts. Prospective cohort studies in Brazil show high rates of hookworm reinfection in malnourished children compared to well-nourished children, despite previous treatment. Additionally, soil-transmitted helminth (STH) infections can worsen the nutritional status of affected populations. Th...

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Ancylostoma ceylanicum Hookworm in the Solomon Islands

Although hookworm is highly prevalent in the Solomon Islands, the species involved are unknown. We initiated this study in response to finding Ancylostoma ceylanicum hookworm in a peacekeeper in Australia who had returned from the Solomon Islands. Kato-Katz fecal surveys performed in 2013 and 2014 in 2 village groups in East Malaita, Solomon Islands, identified hookworm-positive samples. These ...

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In Vitro Il-4, Il-12, and Ifn- Production by Splenocytes from Ancylostoma Ceylanicum Infected Hamsters

The aim of the study was the production of chicken polyclonal antibodies recognising hamster IL-4, IL-12p35, and IFN, which were further used to estimate cytokine concentrations in splenocyte culture supernatants, obtained from three age groups of Ancylostoma ceylanicum infected hamsters. Worm burdens differed significantly among age groups; the younger animals were the more heavily infected. T...

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ژورنال

عنوان ژورنال: Parasite Immunology

سال: 1990

ISSN: 0141-9838,1365-3024

DOI: 10.1111/j.1365-3024.1990.tb00952.x